I would actually suggest either accenting the reptilian or diminishing it. Reptile feet and a tail, for example, or make the torso fuzzy like a spider or hive-surfaced and the hands more insectile.
Somehow blending three species or more visually doesn’t seem to be as popular unless you put in a lot of each. (?) Has promise as RPG characters, particularly if the species is technological. Spiders can already sense ozone or static better than some creatures. They would be believable to reach electronics on a steampunk technological ‘level’ in a game system, except they’d MUCH more likely get power from mill wheels, hamster wheels, mineral-salt-deposits-and-organic-acid batteries, and web-composted carcasses.